Ho Namkoong, M.D. Ph.D. MPH

Publications (English)

• 1.

  Namkoong H※ Omae Y, Asakura T, Ishii M, Suzuki S, Morimoto K, Kawai Y, Emoto K, Oler AJ, Szymanski EP, Yoshida M, Matsuda S, Yagi K, Ishii M, Hase I, Nishimura T, Sasaki Y, Asami T, Shiomi T, Matsubara H, Shimada H, Hamamoto J, Jhun BW, Kim SY, Huh HJ, Won HH, Ato M, Kosaki K, Betsuyaku T, Fukunaga K, Kurashima A, H. Tettelin,Yanai H, Mahasirimongkol S, Olivier KN, Hoshino Y, Koh WJ, Holland SM, Tokunaga K, Hasegawa N. Genome-wide association study in patients with pulmonary Mycobacterium avium complex disease. Eur Respir J. 2021 Feb 4:1902269. (※ Corresponding Author)

• 2.

  Namkoong H*, Horita N, Ebina-Shibuya R. Concern over a COVID-19-related BCG shortage. Int J Tuberc Lung Dis. 2020 Jun 1;24(6):642-643. (* Corresponding Author)

• 3.

  Namkoong H, Ishii M, Fujii H, Yagi K, Asami T, Asakura T, Suzuki S, Hegab AE, Kamata H, Tasaka S, Atarashi K, Nakamoto N, Iwata S, Honda K, Kanai T, Hasegawa N, Koyasu S, Betsuyaku T. Clarithromycin expands CD11b+Gr-1+ cells via the STAT3/Bv8 axis to ameliorate lethal endotoxic shock and post-influenza bacterial pneumonia. PLoS Pathog. 2018 Apr 5;14(4):e1006955.

• 4.

  Namkoong H, Ishii M, Fujii H, Asami T, Yagi K, Suzuki S, Azekawa S, Tasaka S, Hasegawa N, Betsuyaku T. Obesity worsens the outcome of influenza virus infection associated with impaired type I interferon induction in mice. Biochem Biophys Res Commun. 2019 Apr 6.

• 5.

  Namkoong H, Asakura T, Ishii M, Yoda S, Sakagami T, Iwasaki E, Yamagishi Y, Kanai T, Betsuyaku T, Hasegawa N. First report of hepatobiliary Mycobacterium avium infection developing obstructive jaundice in a patient with neutralizing anti-interferon-gamma autoantibodies. New Microbes and New Infections. 2018 Oct 19;27:4-6.

• 6.

  Namkoong H*, Yamazaki M, Ishizaki M, Endo I, Harada N, Aramaki M, Tanaka Y, Kaburagi S, Ichikawa M, Ohata T, Sakaguchi S, Saito F, Nakao A, Yuki H, Mitamura K. Clinical Evaluation of the Immunochromatographic System Using Silver Amplification for the Rapid Detection of Mycoplasma pneumoniae. Sci Rep. 2018 Jan 23;8(1):1430. (* Corresponding Author)

• 7.

  Namkoong H, Ishii M, Mori T, Sugiura H, Tasaka S, Sakurai M, Koda Y, Kato J, Hasegawa N, Okamoto S, Betsuyaku T. Clinical and radiological characteristics of patients with late-onset severe restrictive lung defect after hematopoietic stem cell transplantation. BMC Pulm Med. 2017 Sep 7;17(1):123.

• 8.

  Namkoong H, Morimoto K, Nishimura T, Tanaka H, Sugiura H, Yamada Y, Kurosaki A, Asakura T, Suzuki S, Fujiwara H, Yagi K, Ishii M, Tasaka S, Betsuyaku T, Hoshino Y, Kurashima A, Hasegawa N. Clinical efficacy and safety of multidrug therapy including thrice weekly intravenous amikacin administration for Mycobacterium abscessus pulmonary disease in outpatient settings: a case series. BMC Infect Dis. 2016 Aug 9;16:396.

• 9.

  Namkoong H, Kurashima A, Morimoto K, Hoshino Y, Hasegawa N, Ato M, Mitarai S. Epidemiology of pulmonary nontuberculous mycobacterial disease, Japan. Emerg Infect Dis. 2016 Jun;22(6):1116-7.

• 10.

  Namkoong H, Funatsu Y, Oishi K, Akeda Y, Hiraoka R, Takeshita K, Asami T, Yagi K, Kimizuka Y, Ishii M, Tasaka S, Suzuki Y, Iwata S, Betsuyaku T, Hasegawa N.　Comparison of the immunogenicity and safety of polysaccharide and protein-conjugated pneumococcal vaccines among the elderly aged 80 years or older in Japan: An open-labeled randomized study. Vaccine 2015 Jan 3;33(2):327-32.

• 11.

  Namkoong H, Tasaka S, Akiyama M, Yagi K, Ishii M, Suzuki K, Kohno M, Hasegawa N, Takeuchi T, Betsuyaku T.　Successful resumption of tocilizumab for rheumatoid arthritis after resection of a pulmonary Mycobacterium avium complex lesion: a case report. BMC Pulm Med. 2015 Oct 23;15:126.

• 12.

  Namkoong H, Ishii M, Funatsu Y, Kimizuka Y, Yagi K, Asami T, Asakura T, Suzuki S, Kamo T, Fujiwara H, Tasaka S, Betsuyaku T, Hasegawa N. Theory and strategy for Pneumococcal vaccines in the elderly. Hum Vaccin Immunother. 2016 Feb;12(2):336-43.

• 13.

  Namkoong H, Ishii M, Koizumi M, Betsuyaku T. Fournier's gangrene: a surgical emergency. Infection. 2016 Feb;44(1):143-4.

• 14.

  Namkoong H, Fukumoto K, Hongo I, Hasegawa N. Refractory tenosynovitis with 'rice bodies' in the hand due to Mycobacterium intracellulare. Infection. 2016 Jun;44(3):393-4.

• 15.

  Namkoong H, Ishii M, Tasaka S, Betsuyaku T.　The diagnostic usefulness of 18F-fluorodoxyglucose-positron emission tomography/CT in SAPHO syndrome. BMJ Case Rep. 2015 Mar 2.

• 16.

  Namkoong H, Fujiwara H, Ishii M, Yagi K, Haraguchi M, Matsusaka M, Suzuki S, Asami T, Saito F, Fukunaga K, Tasaka S, Betsuyaku T, Hasegawa N. Immune reconstitution inflammatory syndrome due to Mycobacterium avium complex successfully followed up using 18F-fluorodeoxyglucose positron emission tomography-computed tomography in a patient with human immunodeficiency virus infection: A case report. BMC Med Imaging. 2015 Jul 18;15:24.

• 17.

  Namkoong H, Kameyama Y, Yasuda H, Nakayama S, Kaneko H, Kawashima C, Terajima T, Maezawa K, Hayashi T, Sandoh M, Ishii M, Tasaka S, Kanayama A, Kobayashi I, Betsuyaku T, Kizu J, Iwata S, Sato Y, Hasegawa N.　The efficacy, safety, and pharmacokinetics of biapenem administered thrice daily for the treatment of pneumonia in the elderly. J Infect Chemother. 2014 Jun;20(6):356-60.

• 18.

  Fujiwara Y, Horita N, Namkoong H, Galsky MD. The effect of adding immune checkpoint inhibitors on the risk of pneumonitis for solid tumours: a meta-analysis of phase III randomised controlled trials. Eur J Cancer. 2021 Apr 24;150:168-178.

• 19.

  Yagi K, Ito A, Fujiwara K, Morino E, Hase I, Nakano Y, Asakura T, Furuuchi K, Morita A, Asami T, Namkoong H, Saito F, Morimoto K, Ishii M, Sato Y, Tateno H, Nishio K, Oyamada Y, Fukunaga K, Sugiyama H, Ishida T, Kurashima A, Hasegawa N; Nontuberculous mycobacteriosis and bronchiectasis- Japan Research Consortium (NTM-JRC). Clinical Features and Prognosis of Nontuberculous Mycobacterial Pleuritis: A Multicenter Retrospective Study. Ann Am Thorac Soc. 2021 Apr 8.

• 20.

  Ebina-Shibuya R, Namkoong H, Horita N, Kato H, Hara Y, Kobayashi N, Kaneko T. Hydroxychloroquine and chloroquine for treatment of coronavirus disease 19 (COVID-19): a systematic review and meta-analysis of randomized and non-randomized controlled trials. J Thorac Dis. 2021 Jan;13(1):202-212.

• 21.

  Anan K, Kataoka Y, Okabayashi S, Yamamoto R, Namkoong H, Yamamoto Y. Diagnostic accuracy of Aspergillus-specific antibodies for chronic pulmonary aspergillosis: A systematic review and meta-analysis. Mycoses. 2021 Feb 16.

• 22.

  Kimura T, Namkoong H*. Susceptibility of the obese population to COVID-19. Int J Infect Dis. 2020 Dec;101:380-381. (* Corresponding Author)

• 23.

  Chen H, Horita N, Matsumoto H, Namkoong H, Hara Y, Kobayashi N, Kaneko T. ABO blood group as a risk factor for tuberculosis: A network meta-analysis. Int J Infect Dis. 2021 Mar;104:701-707.

• 24.

  Tateishi Y, Horita N, Namkoong H, Enomoto T, Takeda A, Kaneko T. Postoperative Radiotherapy for Completely Resected Masaoka/Masaoka-Koga Stage II/III Thymoma Improves Overall Survival: An Updated Meta-Analysis of 4746 Patients. J Thorac Oncol. 2021 Apr;16(4):677-685.

• 25.

  Kawakami N, Namkoong H*, Saito F, Ishizaki M, Yamazaki M, Mitamura K. Epidemiology of macrolide-resistant Mycoplasma pneumoniae by age distribution in Japan. J Infect Chemother. 2020 Aug 28:S1341-321X(20)30286-5. (* Corresponding Author)

• 26.

  Azekawa S, Namkoong H*, Mitamura K, Kawaoka Y, Saito F. Co-infection with SARS-CoV-2 and influenza A virus. IDCases. 2020 Apr 21;20:e00775. (* Corresponding Author)

• 27.

  Suzuki S, Ishii M, Asakura T, Namkoong H, Okamori S, Yagi K, Kamata H, Kusumoto T, Kagawa S, Hegab AE, Yoda M, Horiuchi K, Hasegawa N, Betsuyaku T. ADAM17 protects against elastase-induced emphysema by suppressing CD62L+ leukocyte infiltration in mice. Am J Physiol Lung Cell Mol Physiol. 2020 Jun 1;318(6):L1172-L1182.

• 28.

  Koike Y, Namkoong H*, Otake S, Asamura H. Detection of the early stage of spontaneous hemopneumothorax by CT attenuation values. Clin Case Rep. 2020 Apr 20;8(7):1321-1322. (* Corresponding Author)

• 29.

  Ishii M, Terai H, Kabata H, Masaki K, Chubachi S, Tateno H, Nakamura M, Nishio K, Koh H, Watanabe R, Ueda S, Terashima T, Suzuki Y, Yagi K, Miyao N, Minematsu N, Inoue T, Nakachi I, Namkoong H, Okamori S, Ikemura S, Kamata H, Yasuda H, Kawada I, Hasegawa N, Fukunaga K; Keio COVID-19 Research Consortium (K-CORC) and the Keio Donner Project Team. Clinical characteristics of 345 patients with coronavirus disease 2019 in Japan: A multicenter retrospective study. J Infect. 2020 Sep 10:S0163-4453(20)30590-9.

• 30.

  Kawakami N, Namkoong H*, Shimoda M, Kotani H, Fujiwara H, Hasegawa N. Hidden disseminated extracutaneous AIDS-related Kaposi sarcoma. IDCases. 2020 Feb 10;19:e00716. (* Corresponding Author)

• 31.

  Ebina-Shibuya R, Horita N, Namkoong H, Kaneko T. National policies for paediatric universal BCG vaccination were associated with decreased mortality due to COVID-19. Respirology. 2020 Jun 18:10.1111/resp.13885.

• 32.

  Ebina-Shibuya R, Horita N, Namkoong H, Kaneko T. Current national policies for infant universal bacille Calmette-Guérin vaccination were associated with lower mortality from coronavirus disease 2019. Clin Exp Vaccine Res. 2020 Jul;9(2):179-182.

• 33.

  Kawakami N, Kushimoto K, Saito F, Namkoong H*. Cardiac tamponade secondary to empyema. Clin Case Rep. 2020 Feb 5;8(3):574-575. (* Corresponding Author)

• 34.

  Kawakami N, Ohara S, Namkoong H*. Cavitary lesions emerged rapidly in Pseudomonas aeruginosa pneumonia. Clin Case Rep. 2020 Feb 13;8(3):576-577.

• 35.

  Kawakami N, Namkoong H*, Masaki K, Kurebayashi Y, Shimoda M, Kotani H, Fujiwara H, Hasegawa N. IL-6 and G-CSF production resulting from lung cancer in an HIV patient. IDCases. 2020 Jan 9;19:e00693. (* Corresponding Author)

• 36.

  Ebina-Shibuya R, Horita N, Namkoong H, Kaneko T. Current national policies for infant universal bacille Calmette-Guérin vaccination were associated with lower mortality from coronavirus disease 2019. Clin Exp Vaccine Res. 2020 Jul;9(2):179-182.

• 37.

  Asakura T, Kimizuka Y, Nishimura T, Suzuki S, Namkoong H, Masugi Y, Sato Y, Ishii M, Hasegawa N. Serum Krebs von den Lungen-6 level in the disease progression and treatment of Mycobacterium avium complex lung disease. Respirology. 2020 Jun 29. doi: 10.1111/resp.13886.

• 38.

  Kawakami N, Eda H, Nishiura M, Chaya A, Saito F, Namkoong H*. A decade of Gottron's papules, inverse Gottron's papules and mechanic's hand in anti-MDA5-associated interstitial lung disease with clinically amyopathic dermatomyositis. Oxf Med Case Reports. 2020 Jun 25;2020(6):omaa039. (* Corresponding Author)

• 39.

  Kawakami N, Namkoong H*. Buffalo chest syndrome following esophagectomy. Intern Med. 2019 Aug 15;58(16):2413. (* Corresponding Author)

• 40.

  Kawakami N, Namkoong H*, Ohata T, Sakaguchi S, Saito F, Yuki H. A fulminant case of acute respiratory distress syndrome associated with mycoplasma pneumonia treated with nasal high-flow oxygen therapy Case Rep Crit Care. 2018 Oct 21;2018:1067593. (* Corresponding Author)

• 41.

  Asakura T, Suzuki S, Fukano H, Okamori S, Kusumoto T, Uwamino Y, Ogawa T, So M, Uno S, Namkoong H, Yoshida M, Kamata H, Ishii M, Nishimura T, Hoshino Y, Hasegawa N. Sitafloxacin-Containing Regimen for the Treatment of Refractory Mycobacterium avium Complex Lung Disease. Open Forum Infect Dis. 2019 Mar 7;6(4):ofz108.

• 42.

  Ikemura S, Yasuda H, Matsumoto S, Kamada N, Hamamoto J, Masuzawa K, Kobayashi K, Manabe T, Arai D, Nakachi I, Kawada I, Ishioka K, Nakamura M, Namkoong H, Naoki K, Ono F, Araki M, Kanada R, Ma B, Hayashi Y, Mimaki S, Yoh K, Kobayashi S, Kohno T, Okuno Y, Goto K, Tsuchihara K, Soejima K. Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations. Proc Natl Acad Sci U S A 2019 May 14;116(20):10025-10030.

• 43.

  Kimizuka Y, Hoshino Y, Nishimura T, Ishii M, Asami T, Sakakibara Y, Morimoto K, Maeda S, Nakata N, Abe T, Namkoong H, Fujiwara H, Funatsu Y, Yagi K, Fujie T, Inase N, Iwata S, Kurashima A, Betsuyaku T, Hasegawa N; Nontuberculous mycobacteriosis - Japan Research ConsortiumRetrospective evaluation of natural course in mild cases of Mycobacterium avium complex pulmonary disease. Plos One 2019 Apr 25;14(4):e0216034.

• 44.

  Kwak N, Dalcolmo MP, Daley CL, Eather G, Gayoso R, Hasegawa N, Jhun BW, Koh WJ, Namkoong H, Park J, Thomson R, van Ingen J, Zweijpfenning SMH, Yim JJ. Mycobacterium abscessus pulmonary disease: individual patient data meta-analysis. Eur Respir J. 2019 Mar 17.

• 45.

  Kamo T, Tasaka S, Suzuki T, Asakura T, Suzuki S, Yagi K, Namkoong H, Ishii M, Morisaki H, Betsuyaku T. Prognostic values of the Berlin definition criteria, blood lactate level, and fibroproliferative changes on high-resolution computed tomography in ARDS patients. BMC Pulm Med. 2019 Feb 11;19(1):37.

• 46.

  Quantitative assessment of erector spinae muscles in patients with Mycobacterium avium complex lung disease. Asakura T, Yamada Y, Suzuki S, Namkoong H, Okamori S, Kusumoto T, Niijima Y, Ozaki A, Hashimoto M, Yagi K, Kamata H, Funatsu Y, Ishii M, Jinzaki M, Betsuyaku T, Hasegawa N. Respir Med. 2018 Dec;145:66-72.

• 47.

  Kusumoto T, Asakura T, Suzuki S, Okamori S, Namkoong H, Fujiwara H, Yagi K, Kamata H, Ishii M, Betsuyaku T, Hasegawa N. Development of lung cancer in patients with nontuberculous mycobacterial lung disease. Respir Investig. 2019 Mar;57(2):157-164

• 48.

  Asakura T, Ishii M, Namkoong H, Suzuki S, Kagawa S, Yagi K, Komiya T, Hashimoto T, Okamori S, Kamata H, Tasaka S, Kihara A, Hegab EA, Hasegawa N, Betsuyaku T. Sphingosine 1-phosphate Receptor Modulator ONO-4641 Stimulates CD11b+Gr-1+ Cell Expansion and Inhibits Lymphocyte Infiltration in the Lungs to Ameliorate Murine Pulmonary Emphysema. Mucosal Immunol. 2018 Nov;11(6):1606-1620.

• 49.

  Asakura T, Nakagawa T, Suzukia S, Namkoong H, Morimoto K, Ishii M, Kurashima A, Betsuyakua T, Ogawa K, Hasegawa N, ∗Nontuberculous Mycobacteriosis Japan Research Consortium (NTM-JRC) Efficacy and safety of intermittent maintenance therapy after successful treatment of Mycobacterium avium complex lung disease. J Infect Chemother. 2019 Mar;25(3):218-221.

• 50.

  Chaya A, Sato M, Namkoong H, Wada N. Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus infection of the lip. Int J Infect Dis. 2018 Aug 4. pii: S1201-9712(18)34487-4.

• 51.

  Yagi K, Asakura T, Namkoong H, Suzuki S, Asami T, Okamori S, Kusumoto T, Funatsu Y, Kamata H, Nishimura T, Ishii M, Betsuyaku T, Hasegawa N. Association between six-minute walk test parameters and the health-related quality of life in patients with pulmonary Mycobacterium avium complex disease. BMC Pulm Med. 2018 Jul 13;18(1):114.

• 52.

  Kawakami N, Namkoong H*, Ohata T, Sakaguchi S, Saito F, Yuki H. Clinical features of Mycoplasma pneumoniae pneumonia in older adults. Geriatr Gerontol Int. 2018 May;18(5):814-816. (* Corresponding Author)

• 53.

  Asami T, Ishii M, Namkoong H, Yagi K, Tasaka S, Asakura T, Suzuki S, Kamo T, Okamori S, Kamata H, Zhang H, Hegab AE, Hasegawa N, Betsuyaku T. Anti-inflammatory roles of mesenchymal stromal cells during acute Streptococcus pneumoniae pulmonary infection in mice. Cytotherapy. 2018 Mar;20(3):302-313.

• 54.

  Kamata H, Asakura T, Suzuki S, Namkoong H, Yagi K, Funatsu Y, Okamori S, Uno S, Uwamino Y, Fujiwara H, Nishimura T, Ishii M, Betsuyaku T, Hasegawa N. Impact of chronic Pseudomonas aeruginosa infection on health-related quality of life in Mycobacterium avium complex lung disease. BMC Pulm Med. 2017 Dec 13;17(1):198.

• 55.

  Yagi K, Morimoto K, Ishii M, Namkoong H, Okamori S, Asakura T, Suzuki S, Asami T, Uwamino Y, Funatsu Y, Fujiwara H, Kamata H, Nishimura T, Betsuyaku T, Kurashima A, Hasegawa N. Clinical characteristics of pulmonary Mycobacterium lentiflavum disease in adult patients. Int J Infect Dis. 2018 Feb;67:65-69.

• 56.

  Yuge S, Akiyama M, Ishii M, Namkoong H, Yagi K, Nakai Y, Adachi R, Komatsu T. Glycoprotein Nanotube Traps Influenza Virus. Chem Lett. 2017. 46(1):95-97.

• 57.

  Nishimura T, Tamizu E, Uno S, Uwamino Y, Fujiwara H, Nishio K, Nakano Y, Shiono H, Namkoong H, Hoshino Y, Iwata S, Hasegawa N. hsa-miR-346 is a potential serum biomarker of Mycobacterium avium complex pulmonary disease activity. J Infect Chemother. 2017 Aug 18.

• 58.

  Horita, N, Shibata Y, Watanabe H, Namkoong H, Kaneko T. Comparison of antipseudomonal beta-lactams for febrile neutropenia empiric therapy: systematic review and network meta-analysis. Clin Microbiol Infect. 2017 Oct;23(10):723-729.

• 59.

  Yagi K, Ishii M, Namkoong H, Asami T, Iketani O, Asakura T, Suzuki S, Sugiura H, Yamada Y, Nishimura T, Fujiwara H, Funatsu Y, Uwamino Y, Kamo T, Tasaka S, Betsuyaku T, Hasegawa N. The efficacy, safety, and feasibility of inhaled amikacin for the treatment of difficult-to-treat non-tuberculous mycobacterial lung diseases. BMC Infect Dis. 2017 Aug 9;17(1):558.

• 60.

  Asakura T, Namkoong H, Sakagami T, Hasegawa N, Ohkusu K, Nakamura A. Disseminated Mycobacterium genavense Infection in Patient with Adult-Onset Immunodeficiency. Emerg Infect Dis. 2017 Jul;23(7):1208-1210.

• 61.

  Miyawaki M, Naoki K, Yoda S, Nakayama S, Satomi R, Sato T, Ikemura S, Ohgino K, Ishioka K, Arai D, Namkoong H, Otsuka K, Miyazaki M, Tani T, Kuroda A, Nishino M, Yasuda H, Kawada I, Koh H, Nakamura M, Terashima T, Sakamaki F, Sayama K, Betsuyaku T, Soejima K. Erlotinib as second- or third-line treatment in elderly patients with advanced non-small cell lung cancer: Keio Lung Oncology Group Study 001 (KLOG001). Mol Clin Oncol. 2017 Mar;6(3):409-414.

• 62.

  Kuroda A, Hegab AE, Jingtao G, Yamashita S, Hizawa N, Sakamoto T, Yamada H, Suzuki S, Ishii M, Namkoong H, Asakura T, Ozaki M, Yasuda H, Hamamoto J, Kagawa S, Soejima K, Betsuyaku T. Effects of the common polymorphism in the human aldehyde dehydrogenase 2 (ALDH2) gene on the lung. Respir Res. 2017 Apr 21;18(1):69.

• 63.

  Asakura T, Yamada Y, Namkoong H, Suzuki S, Niijima Y, Kamata H, Funatsu Y, Yagi K, Okamori S, Sugiura H, Ishii M, Jinzaki M, Betsuyaku T, Hasegawa N. Impact of cavity and infiltration on pulmonary function and health-related quality of life in pulmonary Mycobacterium avium complex disease: A 3-dimensional computed tomographic analysis. Respir Med. 2017 May;126:9-16.

• 64.

  Asakura T, Hayakawa N, Hasegawa N, Namkoong H, Takeuchi K, Suzuki S, Ishii M, Bestuyaku T, Abe Y, Ouchi M. Long-term Outcome of Pulmonary Resection for Nontuberculous Mycobacterial Pulmonary Disease. Clin Infect Dis. 2017 Mar 25.

• 65.

  Morimoto K, Hasegawa N, Izumi K, Namkoong H, Uchimura K, Yoshiyama T, Hoshino Y, Kurashima A, Sokunaga J, Shibuya S, Shimojima M, Ato M, Mitarai S. A Laboratory-based Analysis of Nontuberculous Mycobacterial Lung Disease in Japan from 2012 to 2013. Ann Am Thorac Soc. 2017 Jan;14(1):49-56.

• 66.

  Funatsu Y, Tasaka S, Asami T, Namkoong H, Fujiwara H, Iketani O, Yagi K, Kimizuka Y, Ishii M, Nishimura T, Ogata H, Iwata S, Betsuyaku T, Hasegawa N. Pharmacokinetics of intravenous peramivir in the airway epithelial lining fluid of healthy volunteers. Antivir Ther. 2016;21(7):621-625.

• 67.

  Morimoto K, Namkoong H, Hasegawa N, Nakagawa T, Morino E, Shiraishi Y, Ogawa K, Izumi K, Takasaki J, Yoshiyama T, Hoshino Y, Matsuda S, Hayashi Y, Sasaki Y, Ishii M, Kurashima A, Nishimura T, Betsuyaku T, Goto H; Nontuberculous Mycobacteriosis Japan Research Consortium. Macrolide-Resistant Mycobacterium avium Complex Lung Disease: Analysis of 102 Consecutive Cases. Ann Am Thorac Soc. 2016 Nov;13(11):1904-1911.

• 68.

  Ueyama M, Asakura T, Morimoto K, Namkoong H, Matsuda S, Osawa T, Ishii M, Hasegawa N, Kurashima A, Goto H. Pneumothorax associated with nontuberculous mycobacteria: A retrospective study of 69 patients. Medicine (Baltimore). 2016 Jul;95(29):e4246.

• 69.

  Suzuki S, Morino E, Ishii M, Namkoong H, Yagi K, Asakura T, Asami T, Fujiwara H, Uwamino Y, Nishimura T, Tasaka S, Betsuyaku T, Takasaki J, Iwata S, Hasegawa N. Clinical characteristics of pulmonary Mycobacterium scrofulaceum disease in 2001-2011: A case series and literature review. J Infect Chemother. 2016 Sep;22(9):611-6.

• 70.

  Asakura T, Nukaga S, Namkoong H, Yagi K, Suzuki S, Ishii M, Tasaka S, Betsuyaku T, Hasegawa N. Blue-Black Trachea as a Result of Minocycline-induced Hyperpigmentation. Am J Respir Crit Care Med. 2016 Feb 1;193(3):e5-6.

• 71.

  Yagi K, Ishii M, Namkoong H, Fujii H, Asami T, Suzuki, S Asakura T, Mizoguchi K, Kamo T, Tasaka S, Chiba N, Ubukata K, Iwata S, Kunkel SL, Hasegawa N, Betsuyaku T. Histone Deacetylase Inhibition Protects Mice against Lethal Post-Influenza Pneumococcal Infection. Crit Care Med. 2016 Oct;44(10).

• 72.

  Horita N, Otsuka T, Haranaga S, Namkoong H, Miki M, Miyashita N, Higa F, Takahashi H, Yoshida M, Kohno S, Kaneko T.Beta-Lactam Plus Macrolides or Beta-Lactam Alone for Community-acquired Pneumonia: Systematic Review and Meta-analysis. Respirology 2016 Oct;21(7):1193-200.

• 73.

  Asakura T, Ishii M, Kikuchi T, Kameyama K, Namkoong H, Nakata N, Sugita K, Tasaka S, Shimizu T, Hoshino Y, Okamoto S, Betsuyaku T, Hasegawa N. Disseminated Mycobacterium marinum Infection With a Destructive Nasal Lesion Mimicking Extranodal NK/T Cell Lymphoma: A Case Report. Medicine (Baltimore). 2016 Mar;95(11):e3131.

• 74.

  Asakura T, Ishii M, Haraguchi M, Kamiyama I, Kohno M, Sakamaki H, Emoto K, Hayashi Y, Sugiura H, Kawada I, Soejima K, Namkoong H, Tasaka S, Hasegawa N, Betsuyaku T. Dry pleurisy complicating solitary pulmonary nodules caused by Mycobacterium avium: a case report. J Med Case Rep. 2015 Oct 26;9:238.

• 75.

  Takahashi S, Ishii M, Namkoong H, Hegab AE, Asami T, Yagi K, Sasaki M, Haraguchi M, Sato M, Kameyama N, Asakura T, Suzuki S, Tasaka S, Iwata S, Hasegawa N, Betsuyaku T. Pneumococcal Infection Aggravates Elastase-Induced Emphysema via Matrix Metalloproteinase 12 Overexpression. J Infect Dis. 2016 Mar 15;213(6):1018-30.

• 76.

  Nishimura T, Fujita-Suzuki Y, Yonemaru M, Ohkusu K, Sakagami T, Carpenter SM, Otsuka Y, Namkoong H, Yano I, Hasegawa N.　Recurrence of Disseminated Mycobacterium avium Complex Disease in a Patient with Anti-Gamma Interferon Autoantibodies by Reinfection. J Clin Microbiol. 2015 Apr;53(4):1436-8.

• 77.

  Horita N, Otsuka T, Haranaga S, Namkoong H, Miki M, Miyashita N, Higa F, Takahashi H, Yoshida M, Kohno S, Kaneko T. Adjunctive Systemic Corticosteroids for Hospitalized Community-Acquired Pneumonia: Systematic Review and Meta-Analysis 2015 Update. Sci Rep. 2015 Sep 16;5:14061.

• 78.

  Asakura T, Funatsu Y, Ishii M, Namkoong H, Yagi K, Suzuki S, Asami T, Kamo T, Fujiwara H, Uwamino Y, Nishimura T, Tasaka S, Betsuyaku T, Hasegawa N. Health-related quality of life is inversely correlated with C-reactive protein and age in Mycobacterium avium complex lung disease: a cross-sectional analysis of 235 patients. Respir Res. 2015 Dec 3;16(1):145.

• 79.

  Kuroda A, Tasaka S, Yagi K, Mochimaru T, Tani T, Namkoong H, Tanaka K, Suzuki Y, Hatano M, Hasegawa N, Okada Y and Betsuyaku T. A case of disseminated cryptococcal infection and concurrent lung tuberculosis in a patient under steroid therapy for interstitial pneumonia. Case Rep Pulmonol. 2015;2015:358926.

• 80.

  Masaki K, Ishii M, Anraku M, Namkoong H, Miyakawa R, Nakajima T, Fukunaga K, Naoki K, Tasaka S, Soejima K, Sayama K, Sugita K, Iwata S, Cui L, Hanaki H, Hasegawa N, Tomoko Betsuyaku T.　Fatal fulminant pneumonia caused by methicillin-sensitive Staphylococcus aureus negative for major high-virulence factors secondary to influenza B virus infection. American Journal of Case Reports 2015 Jul 14;16:454-8.

• 81.

  Yagi K, Ishii M, Namkoong H, Asami T, Fujiwara H, Nishimura T, Saito F, Kimizuka Y, Asakura T, Suzuki S, Kamo T, Tasaka S, Gonoi T, Kamei K, Betsuyaku T, Hasegawa N.　Pulmonary nocardiosis caused by Nocardia cyriacigeorgica in patients with Mycobacterium avium complex lung disease: two case reports. BMC Infect Dis. 2014 Dec 10;14(1):684.

• 82.

  Tasaka S, Kobayashi S, Yagi K, Asami T, Namkoong H, Yamasawa W, Ishii M, Hasegawa N, Betsuyaku T. Serum (1 → 3) β-d-glucan assay for discrimination between Pneumocystis jirovecii pneumonia and colonization. J Infect Chemother. 2014 Jul 24.

• 83.

  Funatsu Y, Hasegawa N, Fujiwara H, Namkoong H, Asami T, Tasaka S, Kimizuka Y, Kamata H, Ishii M, Iketani O, Ogata H, Iwata S, Betsuyaku T. Pharmacokinetics of arbekacin in bronchial epithelial lining fluid of healthy volunteers. J Infect Chemother. 2014 Oct;20(10):607-11.

• 84.

  Asami T, Ishii M*, Fujii H, Namkoong H, Tasaka S, Matsushita K, Ishii K, Yagi K, Fujiwara H, Funatsu Y, Hasegawa N, Betsuyaku T. Modulation of murine macrophage TLR7/8-mediated cytokine expression by mesenchymal stem cell-conditioned medium. Mediators Inflamm. 2013 Sep 28.

• 85.

  Ishii M, Asano K, Namkoong H, Tasaka S, Mizoguchi K, Asami T, Kamata H, Kimizuka Y, Fujiwara H, Funatsu Y, Kagawa S, Miyata J, Ishii K, Nakamura M, Hirai H, Nagata K, Kunkel SL, Hasegawa N, Betsuyaku T. CRTH2 is a critical regulator of neutrophil migration and resistance to polymicrobial sepsis.　J Immunol. 2012 Jun 1;188(11):5655-64.

• 86.

  Tasaka S, Mizoguchi K, Funatsu Y, Namkoong H, Yamasawa W, Ishii M, Hasegawa N, Betsuyaku T. Cytokine profile of bronchoalveolar lavage fluid in patients with combined pulmonary fibrosis and emphysema.　Respirology. 2012 Jul;17(5):814-20.

Education

• 2020    MPH

  Johns Hopkins Bloomberg School of Public Health, Maryland, U.S.A.

• 2018    Ph.D.

  Graduate School of Medicine, Keio University, Tokyo, Japan

• 2007    M.D.

  Keio University School of Medicine, Tokyo, Japan

• 2005       

  Yonsei University College of Medicine, Seoul, Republic of Korea

Volunteer

• 2004

  NGO (Japanese Overseas Christian Cooperative Service) Intern
  Engaged in DOTS program in Tamil Nadu, India

Postdoctoral Training

• 2018-2021

  Post-doctoral Visiting Fellow
  National Institute of Allergy and Infectious Diseases, Maryland, USA

• 2015-2018

  Deputy Director, Department of Pulmonary Medicine, Eiju General Hospital, Tokyo, Japan

• 2010-2015

  Clinical Fellow, Department of Pulmonary Medicine, Division of Medicine, Keio University Hospital, Tokyo, Japan

• 2009-2010

  Senior Residency Program in Internal Medicine, Asahi General Hospital, Chiba, Japan

• 2007-2009

  Residency Program, Asahi General Hospital, Chiba, Japan

Licensure and Certification

• 2016

  General Clinical Oncologist

• 2014

  Board Certified Member of the Japanese Association for Infectious Diseases

• 2013

  Board Certified Member of the Japanese Respiratory Society

• 2013

  Fellow of the Japanese Society of Internal Medicine (FJSIM)

• 2013

  Board Certified Member of the Japanese Society for Tuberculosis

• 2013

  Board Certified Member of the Japanese Society for AIDS Research

• 2013

  Board Certified Member of the Japanese Society of Chemotherapy

• 2010

  Board Certified Member of the Japanese Society of Internal Medicine

• 2007

  Japanese Medical License

Professional Societies

• 2003-present

  Japanese Society for AIDS Research, Member

• 2007-present

  Japanese Society of Internal Medicine, Member

• 2008-present

  Japanese Association for Infectious Diseases, Member

• 2009-present

  Japanese Respiratory Society, Member

• 2010-present

  Japanese Society of Respiratory Endoscopy, Member

• 2010-present

  Japanese Society for Tuberculosis, Member

• 2011-present

  Japanese Society of Chemotherapy, Member

• 2011-present

  Japanese Society for Sleep Research, Member

• 2011-present

  Japanese Society for Immunology, Member

• 2011-present

  Japanese Society for Respiratory Care Medicine, Member

• 2011-present

  American Thoracic Society, Member

Postdoctoral Training

• 1.

  Leading Initiative for Excellent Young Researchers (LEADER)
  Japan Society for the Promotion of Science, 2020/07

• 2.

  The Fellows Award for Research Excellence (FARE)
  National Institutes of Health, 2020

• 3.

  MTPI - Abstract Scholarship
  The Annual International Conference of American Thoracic Society, 2020/05 Philadelphia

• 4.

  The Annual International Conference of American Thoracic Society Asian Pacific Society of Respirology Travel Award
  The Annual International Conference of American Thoracic Society, 2019/05 Dallas

• 5.

  MTPI - Abstract Scholarship
  The Annual International Conference of American Thoracic Society, 2019/05 Dallas

• 6.

  President Award
  The 93rd Annual Meeting of The Japanese Association for Infectious Diseases, 2019/4 Nagoya

• 7.

  Merit Award
  The Tokyo Workshop for Respiratory Pathophysiology, 2016/11, Tokyo

• 8.

  Poster Award
  The 44th Annual Meeting of the Japan Society for Clinical Immunology, 2016/09, Tokyo

• 9.

  International　Trainee Travel Scholarship Award
  The Annual International Conference of American Thoracic Society, 2015/05 Denver

• 10.

  English Mini Symposium Award
  The 55th Annual Meeting of Japanese Respiratory Society, 2015/04 Tokyo

• 11.

  Merit Award
  Society of Novel Action of Macrolide, 2014/07, Tokyo

• 12.

  MTPI - Abstract Scholarship
  The Annual International Conference of American Thoracic Society, 2014/05 San Diego

• 13.

  Young Investigator Travel Award
  The 28th International Congress of Chemotherapy and Infection (ICC2013), 2013/06 Yokohama

• 14.

  President Award
  The 28th Annual Meeting of the Japanese Shock Society, 2013/05 Tokyo

• 15.

  Resident Travel Award
  The 52th Annual Meeting of the Japanese Respiratory Society, 2012/04 Kobe

• 16.

  Biolegend Travel Award
  The Annual International Conference of American Thoracic Society, 2012/05 San Francisco

Research Funding

• 2021-

  APSR multi-country research project

• 2020-present

  Insmed Research Funding

• 2019-present

  AMED Infectious Disease and Immunology Research: U.S.-Japan Cooperative Medical Sciences Program Collaborative Awards, 2019

• 2019-present

  JSPS Overseas Research Fellow Japan Society for the Promotion of Science

• 2019

  NIAID/CBER Intramural Tuberculosis Research Initiative

• 2018

  Research fellow, The Uehara Memorial Foundation

• 2017

  Ohyama Health Foundation

• 2016

  Eiju Fund Research Grant

• 2016

  Keio University Grant-in-Aid for Encouragement of Young Medical Scientists

• 2015-2016

  Grant-in-Aid for Research Activity start-up, Japan Society for the Promotion of Science

• 2015

  Promotion of Medical Sciences and Medical Care, The Ichiro Kanehara Foundation

• 2015

  Daiwa Securities Health Foundation, Health, Medical Care and Welfare-related Aid

• 2015

  Kato Memorial Bioscience Foundation

• 2015

  GlaxoSmithKline Research Grant

• 2015

  Keio University Grant-in-Aid for Encouragement of Young Medical Scientists

• 2013

  Medical Research Grant, Keio Medical Association

• 2013

  Keio University Grant-in-Aid for Encouragement of Young Medical Scientists

• 2013-2014

  Grant-in-Aid for JSPS Fellows, Japan Society for the Promotion of Science

• 2013-2014

  Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science

Presentations (English)

• 1.

  Namkoong H, et al. Host Genetic Analysis of Pulmonary NTM Disease and Non-CF Bronchietasis. The Annual Meeting of American Thoracic Society, 2020/05 Philadelphia (Online)

• 2.

  Namkoong H, et al. Genome-wide association study in patients with pulmonary Mycobacterium avium complex disease. The Annual Meeting of American Thoracic Society, 2019/05 Dallas

• 3.

  Namkoong H, et al. Analysis of Adverse Drug Events in Pulmonary Mycobacterium Avium Complex Disease Using the Japanese Adverse Drug Event Report (JADER) Database, The Annual Meeting of American Thoracic Society, 2018/05 San Diego

• 4.

  Namkoong H, et al. The Epidemiology of Pulmonary Nontuberculous Mycobacterial Disease in Japan. European Respiratory Society International Congress, 2017/09 Milan

• 5.

  Namkoong H, et al. Nationwide Survey on the Epidemiology of Pulmonary Nontuberculous Mycobacterial Disease in Japan. The Annual Meeting of American Thoracic Society, 2015/05 Denver

• 6.

  Namkoong H, et al. Clarithromycin Expands CD11b+Gr-1+Cells to Ameliorate Post-Influenza Pneumococcal Pneumonia. The Annual Meeting of American Thoracic Society, 2015/05 Denver (International　Trainee Travel Scholarship Award)

• 7.

  Namkoong H, et al. Clarithromycin Expands CD11b+Gr-1+Cells to Ameliorate Post-Influenza Pneumococcal Pneumonia. The 55th Annual Meeting of Japanese Respiratory Society, 2015/04 Tokyo (English Mini Symposium Award)

• 8.

  Namkoong H, et al. Clarithromycin Expands CD11b+Gr-1+Cells to Ameliorate Post-Influenza Pneumococcal Pneumonia. Keystone Symposia(Granulomas in Infectious and Non-Infectious Diseases), New Mexico, 2015/01

• 9.

  Namkoong H, et al. Obesity Worsens The Outcome Of Influenza Virus Infection Via Impaired IFN -Beta Induction In Mice. The Annual Meeting of American Thoracic Society, 2014/05 San Diego (MTPI - Abstract Scholarship)

• 10.

  Namkoong H, et al. Clarithromycin expands CD11b+Gr-1+ cells to protect against LPS-induced lethal shock and polymicrobial sepsis. 28th International Congress of Chemotherapy and Infection. 2013/06. Yokohama, Japan. (Young Investigator Travel Award)

• 11.

  Namkoong H, et al. Clarithromycin Expands CD11b+Gr-1+ Cells To Protect Against LPS-Induced Lethal Shock And Polymicrobial Sepsis. The Annual Meeting of American Thoracic Society, 2013/05 Philadelphia

• 12.

  Namkoong H, et al. Clinical Characteristics of Late-Onset Idiopathic Pneumonia Syndrome with Severe Restrictive Lung Deficit After Hematopoietic Stem Cell Transplantation. The Annual Meeting of American Thoracic Society, 2012/05 San Francisco (Biolegend Travel Award)

• 13.

  Namkoong H, et al. The Comparison of Clinical Outcome between Clarithromycin Resistant and Sensitive Mycobacterium avium Complex Pulmonary Disease. The 107th Annual International Conference of American Thoracic Society, 2011/05 Denver

• 14.

  Namkoong H, et al. The extended CAM usage could lead to clinical improvement in clarithromycin resistant Mycobacterium avium Complex Pulmonary Disease. The 51st Annual Meeting of the Japanese Respiratory Society (English Mini Symposium), 2011/04 Tokyo